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                      Akt/PKB (Protein kinase B), a serine/threonine protein kinase with antiapoptotic activity, is one of the major downstream targets of PtdIns(3,4,5)P3 signaling pathway. It contains a pleckstrin homology domain (PH domain) that specifically binds PtdIns(3,4,5)P3 on the plasma membrane. Akt phosphorylation and activation are directly determined by the level of PtdIns(3,4,5)P3 on the plasma membrane, which is regulated by PI3K. Akt consists of three isoforms: PKBα/Akt1, PKBβ/Akt2 and PKBγ/Akt3. Akt isoforms have an N-terminal PH (pleckstrin homology) domain and a kinase domain, which are separated by a 39-amino-acid hinge region. Catalytically active Akt regulates the function of numerous substrates involved in cell survival, growth, proliferation, metabolism and protein synthesis. Akt is a crucial mediator of cell survival and its deactivation is implicated in various stress-induced pathological cell death and degenerative diseases.

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                      842148-40-7

                      BD630887842148-40-798+%

                      ¥1714.001mg

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                      BD37044341276-02-298+%

                      ¥7673.00100mg

                      58066-85-6

                      BD4182058066-85-698+%

                      ¥179.00100mg

                      1386874-06-1

                      BD6302091386874-06-198+%

                      ¥3916.0025mg

                      1032350-13-2

                      BD3016231032350-13-298+%

                      ¥8184.00250mg

                      1431697-86-7

                      BD6302771431697-86-798+%

                      ¥8835.00100mg

                      305834-79-1

                      BD434997305834-79-198+%

                      ¥558.005mg

                      871361-88-5

                      BD630942871361-88-598+%

                      ¥3720.00100mg

                      157716-52-4

                      BD147314157716-52-498+%

                      ¥1850.0010mg

                      552325-73-2

                      BD414942552325-73-298+%

                      ¥3069.0010mg

                      152121-47-6

                      BD150875152121-47-698+%

                      ¥465.005mg

                      1616632-77-9

                      BD3046381616632-77-999+%

                      ¥1532.0025mg

                      1191951-57-1

                      BD3333191191951-57-198+%

                      ¥3181.00100mg

                      28755-03-5

                      BD12766628755-03-598+%

                      ¥539.005mg

                      1396257-94-5

                      BD6302191396257-94-598+%

                      ¥4000.0050mg

                      1313883-00-9

                      BD7648841313883-00-998+%

                      ¥335.001mg

                      1056901-62-2

                      BD2854221056901-62-298+%

                      ¥1254.005mg

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